Cargando...

Putting the brakes on p53-driven apoptosis

Following genotoxic stress, cells activate a complex, kinase-based signaling network to arrest the cell cycle and initiate DNA repair or apoptosis. The tumor suppressor p53 lies at the heart of this DNA damage response. p53 mediates the transactivation of both cell cycle-regulating and pro-apoptotic...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Höpker, Katja, Hagmann, Henning, Khurshid, Safiya, Chen, Shuhua, Schermer, Bernhard, Benzing, Thomas, Reinhardt, Hans Christian
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524207/
https://ncbi.nlm.nih.gov/pubmed/22983126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21997
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!