AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis

Following genotoxic stress, cells activate a complex signalling network to arrest the cell cycle and initiate DNA repair or apoptosis. The tumour suppressor p53 lies at the heart of this DNA damage response. However, it remains incompletely understood, which signalling molecules dictate the choice b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Höpker, Katja, Hagmann, Henning, Khurshid, Safiya, Chen, Shuhua, Hasskamp, Pia, Seeger-Nukpezah, Tamina, Schilberg, Katharina, Heukamp, Lukas, Lamkemeyer, Tobias, Sos, Martin L, Thomas, Roman K, Lowery, Drew, Roels, Frederik, Fischer, Matthias, Liebau, Max C, Resch, Ulrike, Kisner, Tülay, Röther, Fabian, Bartram, Malte P, Müller, Roman Ulrich, Fabretti, Francesca, Kurschat, Peter, Schumacher, Björn, Gaestel, Matthias, Medema, René H, Yaffe, Michael B, Schermer, Bernhard, Reinhardt, H Christian, Benzing, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474921/
https://ncbi.nlm.nih.gov/pubmed/22909821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.236
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados