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Metabolic Fate of SCE-129, a New Antipseudomonal Cephalosporin, After Parenteral Administration in Rats and Dogs
Disposition of [(14)C]SCE-129 was studied in rats and dogs after intramuscular (i.m.) or intravenous (i.v.) injection. In rats, the plasma level of i.m. [(14)C]SCE-129 attained a peak at 15 min after dosing and then declined with a half-life of 35 min, whereas the half-life after an i.v. dose was 26...
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| Veröffentlicht in: | Antimicrob Agents Chemother |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1978
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/686704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.1.137 |
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