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Metabolic Fate of SCE-129, a New Antipseudomonal Cephalosporin, After Parenteral Administration in Rats and Dogs

Disposition of [(14)C]SCE-129 was studied in rats and dogs after intramuscular (i.m.) or intravenous (i.v.) injection. In rats, the plasma level of i.m. [(14)C]SCE-129 attained a peak at 15 min after dosing and then declined with a half-life of 35 min, whereas the half-life after an i.v. dose was 26...

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Библиографические подробности
Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Tanayama, Shigeharu, Yoshida, Kiyoshi, Kanai, Yoshio
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1978
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352417/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/686704/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.1.137
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