Increased expression of adenylyl cyclase 3 in pancreatic islets and central nervous system of diabetic Goto-Kakizaki rats: A possible regulatory role in glucose homeostasis

Adenylyl cyclase 3 (AC3) is expressed in pancreatic islets of the Goto-Kakizaki (GK) rat, a spontaneous animal model of type 2 diabetes (T2D), and also exerts genetic effects on the regulation of body weight in man. In addition to pancreatic islets, the central nervous system (CNS) plays an importan...

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Autores principales: Seed Ahmed, Mohammed, Kovoor, Abraham, Nordman, Sofia, Abu Seman, Norhashimah, Gu, Tianwei, Efendic, Suad, Brismar, Kerstin, Östenson, Claes-Göran, Gu, Harvest F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524141/
https://ncbi.nlm.nih.gov/pubmed/23018249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.22283
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