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Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells

BACKGROUND: MicroRNAs (miRNAs) function as endogenous regulators of biological behaviors of human cancers. Several natural non-coding RNAs are reported to inhibit miRNAs by base-pairing interactions. These phenomena raise questions about the ability of artificial device to regulate miRNAs. The purpo...

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Detalhes bibliográficos
Main Authors: Liu, Yuchen, Han, Yonghua, Zhang, Hu, Nie, Liping, Jiang, Zhimao, Fa, Pingping, Gui, Yaoting, Cai, Zhiming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524115/
https://ncbi.nlm.nih.gov/pubmed/23284967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052280
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