DNA Methylation status of Wnt antagonist SFRP5 can predict the response to the EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer

BACKGROUND: It is well known that genetic alternation of epidermal growth factor receptor (EGFR) plays critical roles in tumorgenesis of lung cancer and can predict outcome of non-small-cell lung cancer treatment, especially the EGFR tyrosine-kinase inhibitors (EGFR-TKIs) therapy. However, it is unc...

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Detalhes bibliográficos
Main Authors: Zhu, Jian, Wang, Yuyan, Duan, Jianchun, Bai, Hua, Wang, Zhijie, Wei, Lai, Zhao, Jun, Zhuo, Minglei, Wang, Shuhang, Yang, Lu, An, Tongtong, Wu, Meina, Wang, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524045/
https://ncbi.nlm.nih.gov/pubmed/23009178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-31-80
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