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Sensing of commensal organisms by the intracellular sensor NOD1 mediates experimental pancreatitis

The intracellular sensor NOD1 has important host defense functions relating to a variety of pathogens. Here we showed that this molecule also participated in the induction of a non-infectious pancreatitis via its response to commensal organisms. Pancreatitis induced by high-dose cerulein (a cholecys...

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Detalhes bibliográficos
Main Authors: Tsuji, Yoshihisa, Watanabe, Tomohiro, Kudo, Masatoshi, Arai, Hidenori, Strober, Warren, Chiba, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523885/
https://ncbi.nlm.nih.gov/pubmed/22902233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.05.024
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