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The Importance of Being Aromatic: Pi interactions in Sodium Symporters

In the LeuT family of sodium solute symporters 13-17% of the residues in transmembrane domains are aromatic. The unique properties of aromatic amino acids enable them to play specialized roles in proteins, but their function in membrane transporters is underappreciated. Here we analyze the π bonding...

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Autors principals: Jiang, Xuan, Loo, Donald D.F., Hirayama, Bruce A., Wright, Ernest M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523751/
https://ncbi.nlm.nih.gov/pubmed/23116249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301329w
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