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Tracking transmitter-gated P2X cation channel activation in vitro and in vivo
We present a noninvasive approach to track activation of ATP-gated P2X receptors and potentially other transmitter-gated cation channels that show calcium fluxes. We genetically engineered rat P2X receptors to carry calcium sensors near the channel pore and tested this as a reporter for P2X(2) recep...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523716/ https://ncbi.nlm.nih.gov/pubmed/18084300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth1144 |
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