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Overexpression of BMP3 in the Developing Skeleton Alters Endochondral Bone Formation Resulting in Spontaneous Rib Fractures
Bone morphogenetic protein-3 (BMP) has been identified as a negative regulator in the skeleton as mice lacking BMP3 have increased bone mass. To further understand how BMP3 mediates bone formation, we created transgenic mice overexpressing BMP3 using the type I collagen promoter. BMP3 transgenic mic...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523674/ https://ncbi.nlm.nih.gov/pubmed/19653325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22048 |
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