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Update on taxane development: new analogs and new formulations

The taxanes (paclitaxel and docetaxel) represent an important class of antineoplastic agents that interfere with microtubule function leading to altered mitosis and cellular death. Paclitaxel (Taxol(®)) was originally extracted from a yew tree (Taxus spp., Taxaceae) a small slow-growing evergreen, c...

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Detalhes bibliográficos
Main Authors: Yared, Jean A, Tkaczuk, Katherine HR
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523563/
https://ncbi.nlm.nih.gov/pubmed/23251087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S28997
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