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Commercial taxane formulations induce stomatocytosis and increase blood viscosity

1. Taxanes are antineoplastic drugs which have cardiovascular side effects of unknown mechanism. We investigated their influence on blood viscosity and erythrocyte morphology. 2. Whole blood was incubated in vitro with increasing concentrations of Taxol®, Taxotere®, paclitaxel (0 – 100 μM) and the v...

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Detalhes bibliográficos
Main Authors: Mark, Michael, Walter, Roland, Meredith, D Osian, Reinhart, Walter H
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573070/
https://ncbi.nlm.nih.gov/pubmed/11704640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704387
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