Sublethal radiation injury uncovers a functional transition during erythroid maturation

OBJECTIVE: Clastogenic injury of the erythroid lineage results in anemia, reticulocytopenia, and transient appearance of micronucleated reticulocytes (MN-RET). However, the MN-RET dose-response in murine models is only linear to 2 Gy total body irradiation (TBI) and paradoxically decreases at higher...

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Main Authors: Peslak, Scott A., Wenger, Jesse, Bemis, Jeffrey C., Kingsley, Paul D., Frame, Jenna M., Koniski, Anne D., Chen, Yuhchyau, Williams, Jacqueline P., McGrath, Kathleen E., Dertinger, Stephen D., Palis, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523099/
https://ncbi.nlm.nih.gov/pubmed/21291953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2011.01.010
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