PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients

BACKGROUND: This study investigated variation in NR1I2 and NR1I3 and its effect on plasma efavirenz levels in HIV/AIDS patients. Variability in plasma drug levels has largely led research on identifying causative variants in drug metabolising enzyme (DME) genes, with little focus on the nuclear rece...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Swart, Marelize, Whitehorn, Heather, Ren, Yuan, Smith, Peter, Ramesar, Rajkumar S, Dandara, Collet
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523080/
https://ncbi.nlm.nih.gov/pubmed/23173844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-112
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker