New In Vitro Model to Study the Effect of Antibiotic Concentration and Rate of Elimination on Antibacterial Activity

A new apparatus is described which serves to investigate the in vitro antibacterial activity of antibiotics as a function of different concentration time curves. The apparatus can be adjusted to simulate the biexponential serum level curves observed in vivo after oral or intramuscular administration...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Grasso, S., Meinardi, G., De Carneri, I., Tamassia, V.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1978
Assuntos:	Pharmacology and Therapeutics
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352290/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/352258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.4.570
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