Pharmacogenetic markers of CYP2B6 associated with efavirenz plasma concentrations in HIV-1 infected Thai adults

AIMS: To investigate the frequency of CYP2B6 polymorphisms and the influence of haplotype structure on plasma efavirenz concentrations in Thai adults with HIV-1 infection. METHODS: Genotyping of nine single nucleotide polymorphisms (SNPs, c.64C>T, c.499C>G, c.516G>T, c.785A>G, c.1375A>...

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Detalhes bibliográficos
Main Authors: Sukasem, Chonlaphat, Cressey, Tim R, Prapaithong, Pattamawan, Tawon, Yardpiroon, Pasomsub, Ekawat, Srichunrusami, Chutatip, Jantararoungtong, Thawinee, Lallement, Marc, Chantratita, Wasun
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Pharmacogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522814/
https://ncbi.nlm.nih.gov/pubmed/22471906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04288.x
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