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Impact of CYP2C19, CYP3A4, ABCB1, and FMO3 genotypes on plasma voriconazole in Thai patients with invasive fungal infections

Voriconazole is the first‐line antifungal choice in the treatment of invasive fungal infections (IFIs). Single nucleotide polymorphisms (SNPs) in drug‐metabolizing and transporter genes may affect voriconazole pharmacokinetics. This study aimed to determine the frequency of the CYP2C19 rs4244285, rs...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Chuwongwattana, Sumonrat, Jantararoungtong, Thawinee, Prommas, Santirat, Medhasi, Sadeep, Puangpetch, Apichaya, Sukasem, Chonlaphat
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596670/
https://ncbi.nlm.nih.gov/pubmed/33124772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.665
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