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Does tumor necrosis factor-alpha (TNF-α) play a role in post-chemotherapy cerebral dysfunction?

Post-chemotherapy treated cancer patients frequently report cognitive difficulties. The biology of this phenomenon is poorly understood, with uncertainty about possible direct toxic effects on the brain, secondary effects from systemic inflammation, host factors/genetic predisposition to cognitive c...

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Detalhes bibliográficos
Main Authors: Ganz, Patricia A., Bower, J.E., Kwan, L., Castellon, S.A., Silverman, D.H.S., Geist, C., Breen, E.C., Irwin, M.R., Cole, S.W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522786/
https://ncbi.nlm.nih.gov/pubmed/22884417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2012.07.015
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