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Scarring trachoma is associated with polymorphism in the tumor necrosis factor alpha (TNF-alpha) gene promoter and with elevated TNF-alpha levels in tear fluid.

Tumor necrosis factor alpha (TNF-alpha) may play a central role in the disease pathogenesis which occurs as a consequence of chlamydial infection. To investigate the importance of TNF-alpha gene promoter polymorphisms and TNF-alpha levels in tear fluid in scarring trachoma, a large matched-pair case...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Conway, D J, Holland, M J, Bailey, R L, Campbell, A E, Mahdi, O S, Jennings, R, Mbena, E, Mabey, D C
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1997
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175081/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9038309/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.3.1003-1006.1997
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