Transcriptional Regulation of the GPX1 Gene by TFAP2C and Aberrant CpG Methylation in Human Breast Cancer

The complexity of gene regulation has created obstacles to defining mechanisms that establish the patterns of gene expression characteristic of the different clinical phenotypes of breast cancer. TFAP2C is a transcription factor, which plays a critical role in the regulation of both estrogen recepto...

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Main Authors: Kulak, Mikhail V., Cyr, Anthony R., Woodfield, George W., Bogachek, Maria, Spanheimer, Philip M., Li, Tiandao, Price, David H., Domann, Frederick E., Weigel, Ronald J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522755/
https://ncbi.nlm.nih.gov/pubmed/22964634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.400
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