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TAp63γ Demethylation Regulates Protein Stability and Cellular Distribution during Neural Stem Cell Differentiation

p63 is a close relative of the p53 tumor suppressor and transcription factor that modulates cell fate. The full-length isoform of p63, containing a transactivation (TA) domain (TAp63) is an essential proapoptotic protein in neural development. The role of p63 in epithelial development is also well e...

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Main Authors: Fonseca, Maria B., Nunes, Ana F., Morgado, Ana L., Solá, Susana, Rodrigues, Cecília M. P.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522631/
https://ncbi.nlm.nih.gov/pubmed/23251711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052417
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