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T-Cell Receptors Binding Orientation over Peptide/MHC Class I Is Driven by Long-Range Interactions

Crystallographic data about T-Cell Receptor – peptide – major histocompatibility complex class I (TCRpMHC) interaction have revealed extremely diverse TCR binding modes triggering antigen recognition. Understanding the molecular basis that governs TCR orientation over pMHC is still a considerable ch...

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Autors principals: Ferber, Mathias, Zoete, Vincent, Michielin, Olivier
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522592/
https://ncbi.nlm.nih.gov/pubmed/23251658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051943
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