The Phosphatase PTP-PEST/PTPN12 Regulates Endothelial Cell Migration and Adhesion, but Not Permeability, and Controls Vascular Development and Embryonic Viability

Protein-tyrosine phosphatase (PTP)-PEST (PTPN12) is ubiquitously expressed. It is essential for normal embryonic development and embryonic viability in mice. Herein we addressed the involvement of PTP-PEST in endothelial cell functions using a combination of genetic and biochemical approaches. By ge...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Souza, Cleiton Martins, Davidson, Dominique, Rhee, Inmoo, Gratton, Jean-Philippe, Davis, Elaine C., Veillette, André
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522311/
https://ncbi.nlm.nih.gov/pubmed/23105101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.387456
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