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Crystal Structure of a Voltage-gated K(+) Channel Pore Module in a Closed State in Lipid Membranes
Voltage-gated K(+) channels underlie the electrical excitability of cells. Each subunit of the functional tetramer consists of the tandem fusion of two modules, an N-terminal voltage-sensor and a C-terminal pore. To investigate how sensor coupling to the pore generates voltage-dependent channel open...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522301/ https://ncbi.nlm.nih.gov/pubmed/23095758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.415091 |
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