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The Plasma Membrane Sialidase NEU3 Regulates the Malignancy of Renal Carcinoma Cells by Controlling β1 Integrin Internalization and Recycling

The human plasma membrane sialidase NEU3 is a key enzyme in the catabolism of membrane gangliosides, is crucial in the regulation of cell surface processes, and has been demonstrated to be significantly up-regulated in renal cell carcinomas (RCCs). In this report, we show that NEU3 regulates β1 inte...

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Detalhes bibliográficos
Main Authors: Tringali, Cristina, Lupo, Barbara, Silvestri, Ilaria, Papini, Nadia, Anastasia, Luigi, Tettamanti, Guido, Venerando, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522280/
https://ncbi.nlm.nih.gov/pubmed/23139422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.407718
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