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Sequence Determinants of GLUT1-mediated Accelerated-exchange Transport: ANALYSIS BY HOMOLOGY-SCANNING MUTAGENESIS
The class 1 equilibrative glucose transporters GLUT1 and GLUT4 are structurally similar but catalyze distinct modes of transport. GLUT1 exhibits trans-acceleration, in which the presence of intracellular sugar stimulates the rate of unidirectional sugar uptake. GLUT4-mediated uptake is unaffected by...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522255/ https://ncbi.nlm.nih.gov/pubmed/23093404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.369587 |
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