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Sequence Determinants of GLUT1-mediated Accelerated-exchange Transport: ANALYSIS BY HOMOLOGY-SCANNING MUTAGENESIS

The class 1 equilibrative glucose transporters GLUT1 and GLUT4 are structurally similar but catalyze distinct modes of transport. GLUT1 exhibits trans-acceleration, in which the presence of intracellular sugar stimulates the rate of unidirectional sugar uptake. GLUT4-mediated uptake is unaffected by...

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書誌詳細
主要な著者: Vollers, Sabrina S., Carruthers, Anthony
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522255/
https://ncbi.nlm.nih.gov/pubmed/23093404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.369587
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