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Paradoxical roles of BST2/Tetherin in promoting IFN-I response and viral infection
Bone marrow stromal antigen-2 (BST2) is a transmembrane protein that prevents virus release from infected cells. It was also reported that BST2 inhibits type-I-interferon (IFN-I) production by plasmacytoid DC (pDC). To determine BST2 impact on antiviral responses in vivo we generated BST2(−/−) mice....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522186/ https://ncbi.nlm.nih.gov/pubmed/22327075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103145 |
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