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RGS16 attenuates pulmonary T helper type 2/T helper type 17 inflammatory responses

The Regulators of G protein signaling (RGS) protein superfamily negatively controls G-protein-coupled receptor (GPCR) signal transduction pathways. RGS16 is enriched in activated/effector T lymphocytes. Here, we show that RGS16 constrains pulmonary inflammation by regulating chemokine-induced T-cell...

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Detalhes bibliográficos
Main Authors: Shankar, Sucharita P., Wilson, Mark S., DiVietro, Jeffrey A., Mentink-Kane, Margaret M., Xie, Zhihui, Wynn, Thomas A., Druey, Kirk M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522182/
https://ncbi.nlm.nih.gov/pubmed/22593615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103781
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