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Why Transcription Factor Binding Sites Are Ten Nucleotides Long
Gene expression is controlled primarily by transcription factors, whose DNA binding sites are typically 10 nt long. We develop a population-genetic model to understand how the length and information content of such binding sites evolve. Our analysis is based on an inherent trade-off between specific...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522170/ https://ncbi.nlm.nih.gov/pubmed/22887818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.143370 |
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