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A Genome-Wide RNAi Screen for Enhancers of par Mutants Reveals New Contributors to Early Embryonic Polarity in Caenorhabditis elegans

The par genes of Caenorhabditis elegans are essential for establishment and maintenance of early embryo polarity and their homologs in other organisms are crucial polarity regulators in diverse cell types. Forward genetic screens and simple RNAi depletion screens have identified additional conserved...

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Detalhes bibliográficos
Main Authors: Morton, Diane G., Hoose, Wendy A., Kemphues, Kenneth J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522167/
https://ncbi.nlm.nih.gov/pubmed/22887819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.143727
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