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Nonrandom X Chromosome Inactivation Is Influenced by Multiple Regions on the Murine X Chromosome

During the development of female mammals, one of the two X chromosomes is inactivated, serving as a dosage-compensation mechanism to equalize the expression of X-linked genes in females and males. While the choice of which X chromosome to inactivate is normally random, X chromosome inactivation can...

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Autori principali: Thorvaldsen, Joanne L., Krapp, Christopher, Willard, Huntington F., Bartolomei, Marisa S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522153/
https://ncbi.nlm.nih.gov/pubmed/22887817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.144477
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