Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt

BACKGROUND: Cancer stem cells (CSC) are believed to play a crucial role in cancer recurrence due to their resistance to conventional chemotherapy and capacity for self-renewal. Recent studies have reported that salinomycin, a livestock antibiotic, selectively targets breast cancer stem cells 100-fol...

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Main Authors: Kuo, Selena Z, Blair, Katherine J, Rahimy, Elham, Kiang, Alan, Abhold, Eric, Fan, Jian-Bing, Wang-Rodriguez, Jessica, Altuna, Xabier, Ongkeko, Weg M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522015/
https://ncbi.nlm.nih.gov/pubmed/23176396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-556
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