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Comparative Nephrotoxicity of Gentamicin and Tobramycin in Rats

A rat model was utilized to compare the nephrotoxic potential of gentamicin and tobramycin. Gentamicin, 40 mg/kg per day, predictably produced renal failure and morphological evidence of proximal tubular necrosis over 14 days of treatment. An identical dosage of tobramycin was associated with only m...

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Bibliografiske detaljer
Main Authors: Gilbert, D. N., Plamp, C., Starr, P., Bennett, W. M., Houghton, D. C., Porter, G.
Format: Artigo
Sprog:Inglês
Udgivet: 1978
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC352181/
https://ncbi.nlm.nih.gov/pubmed/626489
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