Absence of Strand Breaks in Deoxyribonucleic Acid Treated with Metronidazole

The deoxyribonucleic acid (DNA)-degrading potential of metronidazole was evaluated in vitro by three techniques: determination of melting curve, measurement of viscosity, and centrifugation in neutral or alkaline sucrose gradients. Studies were performed on calf thymus DNA and on (3)H-labeled or unl...

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Détails bibliographiques

Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	LaRusso, Nicholas F., Tomasz, Maria, Kaplan, David, Müller, Miklós
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1978
Sujets:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/626487/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.1.19
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