The Polyfunctionality of Human Memory CD8+ T Cells Elicited by Acute and Chronic Virus Infections Is Not Influenced by Age

As humans age, they experience a progressive loss of thymic function and a corresponding shift in the makeup of the circulating CD8+ T cell population from naïve to memory phenotype. These alterations are believed to result in impaired CD8+ T cell responses in older individuals; however, evidence th...

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Detalhes bibliográficos
Main Authors: Lelic, Alina, Verschoor, Chris P., Ventresca, Mario, Parsons, Robin, Evelegh, Carole, Bowdish, Dawn, Betts, Michael R., Loeb, Mark B., Bramson, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521721/
https://ncbi.nlm.nih.gov/pubmed/23271970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003076
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