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Histone H1 compacts DNA under force and during chromatin assembly

Histone H1 binds to linker DNA between nucleosomes, but the dynamics and biological ramifications of this interaction remain poorly understood. We performed single-molecule experiments using magnetic tweezers to determine the effects of H1 on naked DNA in buffer or during chromatin assembly in Xenop...

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Autors principals: Xiao, Botao, Freedman, Benjamin S., Miller, Kelly E., Heald, Rebecca, Marko, John F.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521692/
https://ncbi.nlm.nih.gov/pubmed/23097493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-07-0518
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