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Pharmacokinetics and Tolerance of a Single Twelve-Tablet Dose of Trimethoprim (960 mg)-Sulfamethoxazole (4,800 mg)

To evaluate the potential usefulness of a single large oral dose of trimethoprim-sulfamethoxazole (TMP-SMZ) for the treatment of uncomplicated genitourinary gonorrhea, the pharmacokinetics of a 12-tablet dose containing 960 mg of TMP and 4,800 mg of SMZ were studied in 15 male volunteers, and the to...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Fass, Robert J., Prior, Richard B., Perkins, Robert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1977
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352161/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/883811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.1.102
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