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Pharmacokinetics and Tolerance of a Single Twelve-Tablet Dose of Trimethoprim (960 mg)-Sulfamethoxazole (4,800 mg)

To evaluate the potential usefulness of a single large oral dose of trimethoprim-sulfamethoxazole (TMP-SMZ) for the treatment of uncomplicated genitourinary gonorrhea, the pharmacokinetics of a 12-tablet dose containing 960 mg of TMP and 4,800 mg of SMZ were studied in 15 male volunteers, and the to...

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Detalhes bibliográficos
Main Authors: Fass, Robert J., Prior, Richard B., Perkins, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC352161/
https://ncbi.nlm.nih.gov/pubmed/883811
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