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A Novel Method for Real-Time, Continuous, Fluorescence-Based Analysis of Anti-DNA Abzyme Activity in Systemic Lupus

Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by the production of antibodies against a variety of self-antigens including nucleic acids. These antibodies are cytotoxic, catalytic (hydrolyzing DNA, RNA, and protein), and nephritogenic. Current methods for investigating ca...

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Main Authors: Cavallo, Michelle F., Kats, Anna M., Chen, Ran, Hartmann, James X., Pavlovic, Mirjana
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521466/
https://ncbi.nlm.nih.gov/pubmed/23251791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/814048
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