iLOCi: a SNP interaction prioritization technique for detecting epistasis in genome-wide association studies

BACKGROUND: Genome-wide association studies (GWAS) do not provide a full account of the heritability of genetic diseases since gene-gene interactions, also known as epistasis are not considered in single locus GWAS. To address this problem, a considerable number of methods have been developed for id...

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Hlavní autoři: Piriyapongsa, Jittima, Ngamphiw, Chumpol, Intarapanich, Apichart, Kulawonganunchai, Supasak, Assawamakin, Anunchai, Bootchai, Chaiwat, Shaw, Philip J, Tongsima, Sissades
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
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Proceedings
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521387/
https://ncbi.nlm.nih.gov/pubmed/23281813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S7-S2
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