Quantitative assessment of mitochondrial DNA copies from whole genome sequencing

BACKGROUND: Mitochondrial dysfunction is associated with various aging diseases. The copy number of mtDNA in human cells may therefore be a potential biomarker for diagnostics of aging. Here we propose a new computational method for the accurate assessment of mtDNA copies from whole genome sequencin...

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Detalhes bibliográficos
Main Authors: Chu, Hsueh-Ting, Hsiao, William WL, Tsao, Theresa TH, Chang, Ching-Mao, Liu, Yen-Wenn, Fan, Chen-Chieh, Lin, Han, Chang, Hen-Hong, Yeh, Tze-Jung, Chen, Jen-Chih, Huang, Dun-Ming, Chen, Chaur-Chin, Kao, Cheng-Yan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Proceedings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521385/
https://ncbi.nlm.nih.gov/pubmed/23282223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S7-S5
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