Feasibility of using 454 pyrosequencing for studying quasispecies of the whole dengue viral genome

BACKGROUND: Dengue is the world's most common mosquito-borne viral disease. Poor proofreading by RNA polymerase during its replication results in the accumulation of mutations in its genome. This leads to a diversity of genotypes in the viral population termed quasispecies. Quasispecies play an...

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Bibliographic Details
Main Authors: Chin-inmanu, Kwanrutai, Suttitheptumrong, Aroonroong, Sangsrakru, Duangjai, Tangphatsornruang, Sithichoke, Tragoonrung, Somvong, Malasit, Prida, Tungpradabkul, Sumalee, Suriyaphol, Prapat
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Proceedings
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521222/
https://ncbi.nlm.nih.gov/pubmed/23281804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S7-S7
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