A structurally informed autotransporter platform for efficient heterologous protein secretion and display

BACKGROUND: The self-sufficient autotransporter (AT) pathway, ubiquitous in Gram-negative bacteria, combines a relatively simple protein secretion mechanism with a high transport capacity. ATs consist of a secreted passenger domain and a β-domain that facilitates transfer of the passenger across the...

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Autors principals: Jong, Wouter SP, Soprova, Zora, de Punder, Karin, ten Hagen-Jongman, Corinne M, Wagner, Samuel, Wickström, David, de Gier, Jan-Willem, Andersen, Peter, van der Wel, Nicole N, Luirink, Joen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521207/
https://ncbi.nlm.nih.gov/pubmed/22709508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-85
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