Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli

BACKGROUND: In Escherichia coli phosphoenolpyruvate (PEP) is a key central metabolism intermediate that participates in glucose transport, as precursor in several biosynthetic pathways and it is involved in allosteric regulation of glycolytic enzymes. In this work we generated W3110 derivative strai...

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Hlavní autoři: Meza, Eugenio, Becker, Judith, Bolivar, Francisco, Gosset, Guillermo, Wittmann, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521201/
https://ncbi.nlm.nih.gov/pubmed/22973998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-127
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