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Inhibition of GABA synthesis in the prefrontal cortex increases locomotor activity but does not affect attention in the 5-choice serial reaction time task
Attention deficits are a core cognitive symptom of schizophrenia; the neuropathology underlying these deficits is not known. Attention is regulated, at least in part, by the prefrontal cortex (PFC), a brain area in which pathology of γ-aminobutyric acid (GABA) neurons has been consistently observed...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3521100/ https://ncbi.nlm.nih.gov/pubmed/23022048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.09.009 |
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