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Inhibition of GABA synthesis in the prefrontal cortex increases locomotor activity but does not affect attention in the 5-choice serial reaction time task

Attention deficits are a core cognitive symptom of schizophrenia; the neuropathology underlying these deficits is not known. Attention is regulated, at least in part, by the prefrontal cortex (PFC), a brain area in which pathology of γ-aminobutyric acid (GABA) neurons has been consistently observed...

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Detalhes bibliográficos
Main Authors: Asinof, Samuel K., Paine, Tracie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521100/
https://ncbi.nlm.nih.gov/pubmed/23022048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.09.009
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