F8 haplotype and inhibitor risk: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort

BACKGROUND: Ancestral background, specifically African descent, confers higher risk for development of inhibitory antibodies to factor VIII (FVIII) in hemophilia A. It has been suggested that differences in the distribution of factor VIII gene (F8) haplotypes, and mismatch between endogenous F8 hapl...

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Main Authors: Schwarz, John, Astermark, Jan, Menius, Erika D., Carrington, Mary, Donfield, Sharyne M., Gomperts, Edward D., Nelson, George W., Oldenburg, Johannes, Pavlova, Anna, Shapiro, Amy D., Winkler, Cheryl A., Berntorp, Erik
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521089/
https://ncbi.nlm.nih.gov/pubmed/22958194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hae.12004
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