F8 haplotype and inhibitor risk: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort

BACKGROUND: Ancestral background, specifically African descent, confers higher risk for development of inhibitory antibodies to factor VIII (FVIII) in hemophilia A. It has been suggested that differences in the distribution of factor VIII gene (F8) haplotypes, and mismatch between endogenous F8 hapl...

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Autors principals: Schwarz, John, Astermark, Jan, Menius, Erika D., Carrington, Mary, Donfield, Sharyne M., Gomperts, Edward D., Nelson, George W., Oldenburg, Johannes, Pavlova, Anna, Shapiro, Amy D., Winkler, Cheryl A., Berntorp, Erik
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521089/
https://ncbi.nlm.nih.gov/pubmed/22958194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hae.12004
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